Hm, a last line of Tweak would be the Motherboard, more precisely the Chipset.
Your mileage may vary, but try H.Oda's WPCRedit and WPCRset Tools.
All Chipset Registers (including all performance relevant) are available for Tuning there (BX Chipset .pcr file is included).
Depends on how far you can push the Timings and advanced Tweaks, but a few more % are in for you if you take the time.
(Advanced tweaks include DRAM Turbo-Refresh, Self-Refresh, Burst length and all kinds of mostly RAM related Chipset Timings)
In the end however, when all is apparently running stable, you should put that to a test, e.g. with Prime95. Otherwise, instability or (worst case) data loss could result in the long run.
Upon launching, just cancel the registration Window, and use the program's "Burn in" or "Self/Stress Test" feature to check for errors on Bit level under full load.
http://www.mersenne.org/freesoft.htm